张毅
个人简介：张毅，博士，校聘教授，硕士生导师，山东省“泰山学者”青年专家。2010年在山东师范大学获得理学学士学位，2017年获中国科学院大学理学博士学位。2019-2021年在丹麦哥本哈根大学进行博士后研究。2022年9月进入山东农业大学生命科学学院小麦育种全国重点实验室工作。近年来主持国家自然科学基金青年项目、山东省自然科学基金博士项目，以第一作者在Nature communications、Nature Food、Genome Biology、Plant Journal等学术刊物上发表多篇研究论文。
教育教学工作：
本科生课程：植物生理学、植物生理学实验
博士研究生课程：基因组编辑
科学研究工作：
主要从事植物基因编辑相关研究，能够熟练掌握小麦、水稻、玉米等多种作物的基因编辑。在小麦中建立了一种高效安全的基因编辑技术体系，并将该体系用于小麦产量基因的研究中，明确了基因编辑技术可作为小麦遗传改良的新手段。现阶段主要研究方向为利用基因编辑工具对小麦耐盐性进行改良，以及利用基因编辑工具对作物光合作用相关基因进行改造，提高作物的光合效率。
研究方向：
1. 利用基因编辑技术对小麦耐盐性进行遗传改良。
2. 利用基因编辑工具对作物光合作用相关基因进行改造，提高作物的光合效率。
科研简介：（项目、论文、专利、获奖等情况）
主持科研项目：
1. 国家自然科学基金青年项目，31800304，结题。
2. 山东省自然科学基金项目博士项目，ZR2018BC016，结题。
3. 山东省泰山学者青年专家项目，在研。
发表论文:
1. Li Z1, Zhong F1, Guo J, Chen Z, Song J*, Zhang Y*. (2022). Improving wheat salt tolerance for saline agriculture. Journal of Agricultural and Food Chemistry, 70 (48), 14989-15006.
2. Zhang Y, Pribil M, Palmgren M*, Gao C*. (2020). A CRISPR way for accelerating improvement of food crops. Nature Food, 1, 200-205.
3. Zhang Y, Palmgren M*. (2020). Gene-editing in plants no longer requires tissue culture. Frontiers of Agricultural Science & Engineering, 7, 229-230.
4. Zhang Y, Massel K, Godwin I D, Gao C*. (2018). Applications and potential of genome editing in crop improvement. Genome Biology, 19, 210.
5. Zhang Y1, Li D1, Zhang D, Zhao X, Cao X, Dong L, Liu J, Chen K, Zhang H, Gao C*, Wang D*. (2018). Analysis of the functions of TaGW2 homoeologs in wheat grain weight and protein content traits. Plant Journal, 94, 857-866.
6. Zhang Y, Gao C*. (2017). Recent advances in DNA-free editing and precise base editing in plants. Emerging Topics in Life Sciences, 1, 161-168.
7. Zhang Y1, Liang Z1, Zong Y1, Wang Y, Liu J, Chen K, Qiu J, Gao C*. (2016). Efficient and transgene-free genome editing in wheat through transient expression of CRISPR/Cas9 DNA or RNA. Nature Communications, 7, 12617.
8. Zhang Y, Li J, Gao C*. (2016). Generation of stable transgenic rice (Oryza sativa L.) by Agrobacterium-mediated transformation. Current Protocols in Plant Biology, 1, 235-246.
9. Ji X1, Si X1, Zhang Y, Zhang H, Zhang F, Gao C*. (2018) Conferring DNA virus resistance with high specificity in plants using virus-inducible genome-editing system. Genome Biology, 19, 197.
10. Liang Z, Chen K, Yan Y, Zhang Y, Gao C*. (2018). Genotyping genome-edited mutations in plants using CRISPR ribonucleoprotein complexes. Plant Biotechnology Journal, 16, 2053-2062.
11. Liang Z1, Chen K1, Zhang Y, Liu J, Yin K, Qiu J, Gao C*. (2018). Genome editing of bread wheat using biolistic delivery of CRISPR/Cas9 in vitro transcripts or ribonucleoproteins. Nature Protocols, 13, 413-430.
12. Meng X1, Yu H1, Zhang Y, Zhuang F, Song X, Gao S, Gao C*, Li J*. (2017). Construction of a genome-wide mutant library in rice using CRISPR/Cas9. Molecular Plant, 10, 1238-1241.
13. Liang Z1, Chen K1, Li T, Zhang Y, Wang Y, Zhao Q, Liu J, Zhang H, Liu C, Ran Y, Gao C*. (2017). Efficient DNA-free genome editing of bread wheat using CRISPR/Cas9 ribonucleoprotein complexes. Nature Communications, 8, 14261.
14. Shan Q, Zhang Y, Chen K, Zhang K, Gao C*. (2015). Creation of fragrant rice by targeted knockout of the OsBADH2 gene using TALEN technology. Plant Biotechnology Journal, 13, 791-800.
15. Ji X1, Zhang H1, Zhang Y, Wang Y, Gao C*. (2015). Establishing a CRISPR-Cas-like immue system conferring DNA virus resistance in plants. Nature Plants, 1, 15144.
16. Zhang K1, Liu J1, Zhang Y, Yang Z, Gao, C*. (2015). Biolistic genetic transformation of a wide range of Chinese elite wheat (Triticum aestivum L.) varieties. Journal of Genetics and Genomics, 42, 39-42.
17. Wang S, Li S, Liu Q, Wu K, Zhang J, Wang S, Wang Y, Chen X, Zhang Y, Gao C, Wang F, Huang H, Fu X*. (2015). The OsSPL16-GW7 regulatory module determines grain shape and simultaneously improves rice yield and grain quality. Nature Genetics, doi:10.1038/ng.3352.
18. Wang Y1, Cheng X1, Shan Q, Zhang Y, Liu J, Gao C*, Qiu J*. (2014) Simultaneous editing of three homoeoalleles in hexaploid bread wheat confers heritable resistance to powdery mildew. Nature Biotechnology, 32, 947-951.
19. Shan Q1, Wang Y1, Li J1, Zhang Y, Chen K, Liang Z, Zhang K, Liu J, Qiu J*, Gao C*. (2013). Targeted genome modification of crop plants using a CRISPR-Cas system. Nature Biotechnology, 31, 686-688.
20. Shan Q1, Wang Y1, Chen K1, Liang Z, Li J, Zhang Y, Zhang K, Liu J, Voytas D F, Zheng X, Zhang Y*, Gao C*. (2013). Rapid and efficient gene modification in rice and Brachypodium using TALENs. Molecular Plant, 6, 1365-1368.
授权专利：
1. 一种提高小麦产量的方法，专利号：CN106978436B，发明人：高彩霞，张毅（已授权）。
2. A method for site-directed modification of whole plant through gene transient expression. Patent number: PCT/CN2016/072352. Patent inventor: Caixia Gao, Yi Zhang, Zhongyi Wu, Kang Zhang (published in many counties and granted in Australia and Eurasian Patent Organization).
联系方式：15106909932
通讯地址：泰安市泰山区岱宗大街61号，山东农业大学
联系电话: 15106909932
E-mail: yizhang@sdau.edu.cn
联系地址：登高楼103办公室
